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Converts methyleneTHF into methylTHF for the methionine-synthesis.Genetic variations increase the risk of thrombosis and causes a higher homocysteine level.
Mutant has a higher risk of obesity (3 times more). The genetic variations of the Apolipoprotein E (ApoE) higher risk of atherosclerosis and diseases at the coronary artery. Other genetic variations in the interleukins increase the risk of a periodontitis. There will be a risk of thrombosis if the variation is in the clotting factors (Factor II, Factor V and MTHFR).